Defining the critical role of osteoclasts in multiple myeloma cell growth and activation in bone


Lead Researcher: Professor Peter Croucher

Institution: Garvan Institute of Medical Research (NSW)

Funding: $360,000

Funding Duration: 2014 - 2016

The Research

Multiple myeloma is an incurable cancer of blood cells that grow in bone marrow. In the early stages myeloma cells move to bone and stay dormant until activated to grow. We have developed a new technique to see single myeloma cells in living bone for the first time. We will use this to study myeloma in the early stages to see whether normal bone cells switch on these dormant cells and cause the cancer to grow. We can then use bone drugs to stop myeloma from growing in patients with this disease.


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