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Lead Researcher: Associate Professor Andrew Spillane
Institution: Melanoma Institute Australia
Funding: $360,000
Funding Duration: 2015 – 2017
The Research
In its advanced stages, melanoma can spread to lymph nodes of the body, such as the inguinal lymph nodes of the groin. An international, multicentre, randomised clinical trial commenced in 2015, and sought to address the question of whether to perform inguinal (IL) or ilio-inguinal lymphadenectomy (I-IL) for patients with inguinal nodal metastatic melanoma who have no clinical or imaging evidence of pelvic disease. I-IL is a more surgically extensive option in which extra lymph nodes are removed.
The EAGLE FM trial, led by Professor Andrew Spillane of Melanoma Institute Australia and sponsored by Melanoma and Skin Cancer Trials included participants from 14 hospitals across Australia, Brazil, Italy, the Netherlands, Slovenia and the United Kingdom and followed these participants for five years. Results from the EAGLE FM trial has recently been published in the Annals of Surgical Oncology (Read the paper by Dr Teresa Lee).
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